RAB21 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RAB21

RAB21, member RAS oncogene family. (225 aa)

Predicted Functional Partners:

ENSNLEP00000024537

0.959

RABGEF1

0.959

ANKRD27

0.855

SBF2

0.742

NCAPD3

0.723

MAMDC2

0.695

CHM

0.691

GAPVD1

0.678

SBF1

0.676

GDI1

0.661

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD27	CHM	ENSNLEP00000043215	ENSNLEP00000028284	Ankyrin repeat domain 27.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.411
ANKRD27	GDI1	ENSNLEP00000043215	ENSNLEP00000017321	Ankyrin repeat domain 27.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.435
ANKRD27	RAB21	ENSNLEP00000043215	ENSNLEP00000005357	Ankyrin repeat domain 27.	RAB21, member RAS oncogene family.	0.855
CHM	ANKRD27	ENSNLEP00000028284	ENSNLEP00000043215	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ankyrin repeat domain 27.	0.411
CHM	ENSNLEP00000024537	ENSNLEP00000028284	ENSNLEP00000024537	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	A20-type domain-containing protein.	0.883
CHM	GAPVD1	ENSNLEP00000028284	ENSNLEP00000034070	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	GTPase activating protein and VPS9 domains 1.	0.494
CHM	GDI1	ENSNLEP00000028284	ENSNLEP00000017321	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.605
CHM	RAB21	ENSNLEP00000028284	ENSNLEP00000005357	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB21, member RAS oncogene family.	0.691
CHM	RABGEF1	ENSNLEP00000028284	ENSNLEP00000035419	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB guanine nucleotide exchange factor 1.	0.883
CHM	SBF1	ENSNLEP00000028284	ENSNLEP00000024521	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	SET binding factor 1.	0.479
CHM	SBF2	ENSNLEP00000028284	ENSNLEP00000021340	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	SET binding factor 2.	0.479
ENSNLEP00000024537	CHM	ENSNLEP00000024537	ENSNLEP00000028284	A20-type domain-containing protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.883
ENSNLEP00000024537	GAPVD1	ENSNLEP00000024537	ENSNLEP00000034070	A20-type domain-containing protein.	GTPase activating protein and VPS9 domains 1.	0.564
ENSNLEP00000024537	GDI1	ENSNLEP00000024537	ENSNLEP00000017321	A20-type domain-containing protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.895
ENSNLEP00000024537	RAB21	ENSNLEP00000024537	ENSNLEP00000005357	A20-type domain-containing protein.	RAB21, member RAS oncogene family.	0.959
ENSNLEP00000024537	RABGEF1	ENSNLEP00000024537	ENSNLEP00000035419	A20-type domain-containing protein.	RAB guanine nucleotide exchange factor 1.	0.620
GAPVD1	CHM	ENSNLEP00000034070	ENSNLEP00000028284	GTPase activating protein and VPS9 domains 1.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.494
GAPVD1	ENSNLEP00000024537	ENSNLEP00000034070	ENSNLEP00000024537	GTPase activating protein and VPS9 domains 1.	A20-type domain-containing protein.	0.564
GAPVD1	GDI1	ENSNLEP00000034070	ENSNLEP00000017321	GTPase activating protein and VPS9 domains 1.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.475
GAPVD1	RAB21	ENSNLEP00000034070	ENSNLEP00000005357	GTPase activating protein and VPS9 domains 1.	RAB21, member RAS oncogene family.	0.678

page 1 of 3

Server load: low (40%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About