STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAIPNLR family apoptosis inhibitory protein. (1257 aa)    
Predicted Functional Partners:
NLRC4
NLR family CARD domain containing 4.
  
 
0.952
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 0.830
AIM2
Absent in melanoma 2.
      
 0.820
TRADD
TNFRSF1A associated via death domain.
   
 0.814
NLRP1
NLR family pyrin domain containing 1.
    
 0.800
DIABLO
Uncharacterized protein.
    
 0.772
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
 0.757
MEFV
MEFV innate immuity regulator, pyrin.
   
 
 0.756
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
   
 0.751
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.738
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.