Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G1QWQ9_NOMLEHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)    
Predicted Functional Partners:
LOC100593400
Histone H3; Belongs to the histone H3 family.
   
 0.788
H3C13
Histone H3; Belongs to the histone H3 family.
   
 0.788
H2BC18
Histone H2B; Belongs to the histone H2B family.
   
 0.743
H2AC6
Histone H2A; Belongs to the histone H2A family.
   
 0.731
H2BC15
Histone H2B; Belongs to the histone H2B family.
   
 0.720
H2AC7
Histone H2A; Belongs to the histone H2A family.
   
 0.710
H3-4
Histone H3; Belongs to the histone H3 family.
   
 0.702
LOC100599068
Histone H3; Belongs to the histone H3 family.
   
 0.685
ENSNLEP00000034023
Histone H3; Belongs to the histone H3 family.
   
 0.685
LOC100583243
Histone H3; Belongs to the histone H3 family.
   
 0.685
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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