TNS3 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCAR1	PTK2	ENSNLEP00000041451	ENSNLEP00000034458	BCAR1 scaffold protein, Cas family member.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.994
BCAR1	TLN1	ENSNLEP00000041451	ENSNLEP00000034100	BCAR1 scaffold protein, Cas family member.	Talin 1.	0.705
BCAR1	TNS3	ENSNLEP00000041451	ENSNLEP00000005388	BCAR1 scaffold protein, Cas family member.	Tensin 3.	0.759
EGFR	ERBB2	ENSNLEP00000035792	ENSNLEP00000048945	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.996
EGFR	HGF	ENSNLEP00000035792	ENSNLEP00000023996	Receptor protein-tyrosine kinase.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.817
EGFR	MET	ENSNLEP00000035792	ENSNLEP00000024614	Receptor protein-tyrosine kinase.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.956
EGFR	MST1R	ENSNLEP00000035792	ENSNLEP00000008444	Receptor protein-tyrosine kinase.	Macrophage stimulating 1 receptor.	0.727
EGFR	PTK2	ENSNLEP00000035792	ENSNLEP00000034458	Receptor protein-tyrosine kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.949
EGFR	TNS3	ENSNLEP00000035792	ENSNLEP00000005388	Receptor protein-tyrosine kinase.	Tensin 3.	0.860
ERBB2	EGFR	ENSNLEP00000048945	ENSNLEP00000035792	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.996
ERBB2	HGF	ENSNLEP00000048945	ENSNLEP00000023996	Receptor protein-tyrosine kinase.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.762
ERBB2	MET	ENSNLEP00000048945	ENSNLEP00000024614	Receptor protein-tyrosine kinase.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.891
ERBB2	MST1R	ENSNLEP00000048945	ENSNLEP00000008444	Receptor protein-tyrosine kinase.	Macrophage stimulating 1 receptor.	0.867
ERBB2	PTK2	ENSNLEP00000048945	ENSNLEP00000034458	Receptor protein-tyrosine kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.869
ERBB2	TNS3	ENSNLEP00000048945	ENSNLEP00000005388	Receptor protein-tyrosine kinase.	Tensin 3.	0.655
GAK	MET	ENSNLEP00000001124	ENSNLEP00000024614	Cyclin G associated kinase.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.476
GAK	MST1R	ENSNLEP00000001124	ENSNLEP00000008444	Cyclin G associated kinase.	Macrophage stimulating 1 receptor.	0.476
GAK	SPRTN	ENSNLEP00000001124	ENSNLEP00000002537	Cyclin G associated kinase.	SprT-like N-terminal domain.	0.672
GAK	TNS3	ENSNLEP00000001124	ENSNLEP00000005388	Cyclin G associated kinase.	Tensin 3.	0.687
HGF	EGFR	ENSNLEP00000023996	ENSNLEP00000035792	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Receptor protein-tyrosine kinase.	0.817

page 1 of 4

Server load: low (16%) [HD]

Share

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About