close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.749
CISH
Cytokine inducible SH2 containing protein.
     
 0.684
ENSNLEP00000035510
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.679
LOC100581166
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.679
ELOC
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.678
MYCBP2
MYC binding protein 2.
    
 
 0.600
RNF7
Ring finger protein 7.
    
 0.596
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.571
CCDC22
Coiled-coil domain containing 22.
   
 
  0.558
UBA3
Ubiquitin like modifier activating enzyme 3.
   
 
  0.556
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.