Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG4Pleckstrin homology and RhoGEF domain containing G4. (1192 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.737
RABIF
RAB interacting factor.
      
 0.668
SPTBN2
Spectrin beta chain; Belongs to the spectrin family.
    
 
 0.607
BEAN1
Brain expressed associated with NEDD4 1.
      
 0.555
KCTD19
Potassium channel tetramerization domain containing 19.
      
 0.549
SLAMF8
SLAM family member 8.
      
 0.519
BUD13
BUD13 homolog.
      
 0.500
ITSN1
Intersectin 1.
     
 0.499
SIPA1L1
Signal induced proliferation associated 1 like 1.
      
 0.497
LY6G6F
Lymphocyte antigen 6 family member G6F.
      
 0.496
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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