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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)    
Predicted Functional Partners:
CCNG2
Cyclin G2; Belongs to the cyclin family.
     
 
0.900
GAK
Cyclin G associated kinase.
   
 0.780
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.724
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
   
 0.697
MDM2
MDM2 proto-oncogene.
   
 0.697
CDK17
Cyclin dependent kinase 17.
   
 0.691
CDC20B
Cell division cycle 20B.
   
 0.679
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.679
CDC20
Cell division cycle 20.
   
 0.679
ENSNLEP00000028618
WD_REPEATS_REGION domain-containing protein.
   
 0.679
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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