Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | EP300 | ENSNLEP00000008823 | ENSNLEP00000035934 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | E1A binding protein p300. | 0.694 |
| ATM | HIPK1 | ENSNLEP00000008823 | ENSNLEP00000031261 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Homeodomain interacting protein kinase 1. | 0.460 |
| ATM | KCTD2 | ENSNLEP00000008823 | ENSNLEP00000000637 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Uncharacterized protein. | 0.515 |
| ATM | TP63 | ENSNLEP00000008823 | ENSNLEP00000032932 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.829 |
| ATM | UBE2I | ENSNLEP00000008823 | ENSNLEP00000010420 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.696 |
| CBFB | CREBBP | ENSNLEP00000005199 | ENSNLEP00000011912 | Core-binding factor subunit beta. | CREB binding protein. | 0.607 |
| CBFB | EP300 | ENSNLEP00000005199 | ENSNLEP00000035934 | Core-binding factor subunit beta. | E1A binding protein p300. | 0.751 |
| CBFB | HIPK1 | ENSNLEP00000005199 | ENSNLEP00000031261 | Core-binding factor subunit beta. | Homeodomain interacting protein kinase 1. | 0.512 |
| CREBBP | CBFB | ENSNLEP00000011912 | ENSNLEP00000005199 | CREB binding protein. | Core-binding factor subunit beta. | 0.607 |
| CREBBP | EP300 | ENSNLEP00000011912 | ENSNLEP00000035934 | CREB binding protein. | E1A binding protein p300. | 0.998 |
| CREBBP | HIPK1 | ENSNLEP00000011912 | ENSNLEP00000031261 | CREB binding protein. | Homeodomain interacting protein kinase 1. | 0.475 |
| CREBBP | KCTD2 | ENSNLEP00000011912 | ENSNLEP00000000637 | CREB binding protein. | Uncharacterized protein. | 0.448 |
| CREBBP | MECP2 | ENSNLEP00000011912 | ENSNLEP00000036087 | CREB binding protein. | MBD domain-containing protein. | 0.550 |
| CREBBP | PML | ENSNLEP00000011912 | ENSNLEP00000046595 | CREB binding protein. | Uncharacterized protein. | 0.866 |
| CREBBP | TP63 | ENSNLEP00000011912 | ENSNLEP00000032932 | CREB binding protein. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.594 |
| CREBBP | UBE2I | ENSNLEP00000011912 | ENSNLEP00000010420 | CREB binding protein. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.842 |
| DCAF7 | HIPK1 | ENSNLEP00000005405 | ENSNLEP00000031261 | DDB1 and CUL4 associated factor 7. | Homeodomain interacting protein kinase 1. | 0.639 |
| EP300 | ATM | ENSNLEP00000035934 | ENSNLEP00000008823 | E1A binding protein p300. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.694 |
| EP300 | CBFB | ENSNLEP00000035934 | ENSNLEP00000005199 | E1A binding protein p300. | Core-binding factor subunit beta. | 0.751 |
| EP300 | CREBBP | ENSNLEP00000035934 | ENSNLEP00000011912 | E1A binding protein p300. | CREB binding protein. | 0.998 |
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