| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AARSD1 | PPP1R14B | ENSNLEP00000014444 | ENSNLEP00000005926 | Uncharacterized protein. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.556 |
| AARSD1 | TBCB | ENSNLEP00000014444 | ENSNLEP00000041374 | Uncharacterized protein. | Tubulin folding cofactor B. | 0.752 |
| APIP | GNPDA1 | ENSNLEP00000030645 | ENSNLEP00000035356 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | Glucosamine-6-phosphate isomerase. | 0.574 |
| APIP | MSGN1 | ENSNLEP00000030645 | ENSNLEP00000022680 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | Mesogenin 1. | 0.542 |
| APIP | PPP1R14B | ENSNLEP00000030645 | ENSNLEP00000005926 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.542 |
| GNPDA1 | APIP | ENSNLEP00000035356 | ENSNLEP00000030645 | Glucosamine-6-phosphate isomerase. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | 0.574 |
| GNPDA1 | MSGN1 | ENSNLEP00000035356 | ENSNLEP00000022680 | Glucosamine-6-phosphate isomerase. | Mesogenin 1. | 0.542 |
| GNPDA1 | PPP1R14B | ENSNLEP00000035356 | ENSNLEP00000005926 | Glucosamine-6-phosphate isomerase. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.542 |
| MAP2K5 | PPP1R14B | ENSNLEP00000015873 | ENSNLEP00000005926 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.537 |
| MSGN1 | APIP | ENSNLEP00000022680 | ENSNLEP00000030645 | Mesogenin 1. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | 0.542 |
| MSGN1 | GNPDA1 | ENSNLEP00000022680 | ENSNLEP00000035356 | Mesogenin 1. | Glucosamine-6-phosphate isomerase. | 0.542 |
| MSGN1 | PPP1R14B | ENSNLEP00000022680 | ENSNLEP00000005926 | Mesogenin 1. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.542 |
| PPP1CA | PPP1CC | ENSNLEP00000007753 | ENSNLEP00000003868 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.997 |
| PPP1CA | PPP1R14B | ENSNLEP00000007753 | ENSNLEP00000005926 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.610 |
| PPP1CA | PPP1R14D | ENSNLEP00000007753 | ENSNLEP00000003981 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Uncharacterized protein. | 0.414 |
| PPP1CC | PPP1CA | ENSNLEP00000003868 | ENSNLEP00000007753 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.997 |
| PPP1CC | PPP1R14B | ENSNLEP00000003868 | ENSNLEP00000005926 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Protein phosphatase 1 regulatory inhibitor subunit 14B. | 0.670 |
| PPP1R14B | AARSD1 | ENSNLEP00000005926 | ENSNLEP00000014444 | Protein phosphatase 1 regulatory inhibitor subunit 14B. | Uncharacterized protein. | 0.556 |
| PPP1R14B | APIP | ENSNLEP00000005926 | ENSNLEP00000030645 | Protein phosphatase 1 regulatory inhibitor subunit 14B. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | 0.542 |
| PPP1R14B | GNPDA1 | ENSNLEP00000005926 | ENSNLEP00000035356 | Protein phosphatase 1 regulatory inhibitor subunit 14B. | Glucosamine-6-phosphate isomerase. | 0.542 |
