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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNTFRCiliary neurotrophic factor receptor. (372 aa)    
Predicted Functional Partners:
CNTF
Ciliary neurotrophic factor.
    
 0.999
LIFR
LIF receptor subunit alpha.
    
 0.990
CLCF1
Uncharacterized protein.
    
 0.988
IL6
Uncharacterized protein.
   
 0.953
IL27RA
Interleukin 27 receptor subunit alpha.
   
 0.929
IL11
Uncharacterized protein.
     
 0.928
IL6ST
Interleukin 6 signal transducer.
   
0.910
CTF1
Cardiotrophin 1.
     
 0.902
LIF
LIF interleukin 6 family cytokine.
     
 0.872
TYK2
Tyrosine-protein kinase.
    
 0.868
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.