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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1056 aa)    
Predicted Functional Partners:
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
    
 
 0.885
ARL8B
ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.741
GABARAP
GABA type A receptor-associated protein.
    
 
 0.675
RAB7A
RAB7A, member RAS oncogene family.
    
 
 0.654
GABARAPL2
GABA type A receptor associated protein like 2.
    
 
 0.635
GABARAPL1
GABA type A receptor associated protein like 1.
    
 
 0.604
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
      
 0.602
CLCN7
CBS domain-containing protein.
      
 0.598
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.586
SNAP29
t-SNARE coiled-coil homology domain-containing protein.
      
 0.565
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.