| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSNLEP00000031915 | KCTD2 | ENSNLEP00000031915 | ENSNLEP00000000637 | Ubiquitin-like domain-containing protein. | Uncharacterized protein. | 0.721 |
| ENSNLEP00000031915 | TOP1 | ENSNLEP00000031915 | ENSNLEP00000007880 | Ubiquitin-like domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.595 |
| ENSNLEP00000031915 | TOPORS | ENSNLEP00000031915 | ENSNLEP00000048031 | Ubiquitin-like domain-containing protein. | TOP1 binding arginine/serine rich protein. | 0.669 |
| ENSNLEP00000031915 | UBE2I | ENSNLEP00000031915 | ENSNLEP00000010420 | Ubiquitin-like domain-containing protein. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.966 |
| ENSNLEP00000046801 | TOPORS | ENSNLEP00000046801 | ENSNLEP00000048031 | Protein kinase domain-containing protein. | TOP1 binding arginine/serine rich protein. | 0.713 |
| ENSNLEP00000046801 | UBE2D1 | ENSNLEP00000046801 | ENSNLEP00000014947 | Protein kinase domain-containing protein. | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. | 0.468 |
| KCTD2 | ENSNLEP00000031915 | ENSNLEP00000000637 | ENSNLEP00000031915 | Uncharacterized protein. | Ubiquitin-like domain-containing protein. | 0.721 |
| KCTD2 | SUMO1 | ENSNLEP00000000637 | ENSNLEP00000046412 | Uncharacterized protein. | Small ubiquitin-related modifier. | 0.721 |
| KCTD2 | TOP1 | ENSNLEP00000000637 | ENSNLEP00000007880 | Uncharacterized protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.692 |
| KCTD2 | TOPORS | ENSNLEP00000000637 | ENSNLEP00000048031 | Uncharacterized protein. | TOP1 binding arginine/serine rich protein. | 0.609 |
| PLK1 | TOPORS | ENSNLEP00000014587 | ENSNLEP00000048031 | Serine/threonine-protein kinase PLK. | TOP1 binding arginine/serine rich protein. | 0.784 |
| PLK1 | UBE2D1 | ENSNLEP00000014587 | ENSNLEP00000014947 | Serine/threonine-protein kinase PLK. | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. | 0.468 |
| SPIN3 | TOPORS | ENSNLEP00000024660 | ENSNLEP00000048031 | Uncharacterized protein. | TOP1 binding arginine/serine rich protein. | 0.771 |
| SUMO1 | KCTD2 | ENSNLEP00000046412 | ENSNLEP00000000637 | Small ubiquitin-related modifier. | Uncharacterized protein. | 0.721 |
| SUMO1 | TOP1 | ENSNLEP00000046412 | ENSNLEP00000007880 | Small ubiquitin-related modifier. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.595 |
| SUMO1 | TOPORS | ENSNLEP00000046412 | ENSNLEP00000048031 | Small ubiquitin-related modifier. | TOP1 binding arginine/serine rich protein. | 0.743 |
| SUMO1 | UBE2I | ENSNLEP00000046412 | ENSNLEP00000010420 | Small ubiquitin-related modifier. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.995 |
| TOP1 | ENSNLEP00000031915 | ENSNLEP00000007880 | ENSNLEP00000031915 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-like domain-containing protein. | 0.595 |
| TOP1 | KCTD2 | ENSNLEP00000007880 | ENSNLEP00000000637 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Uncharacterized protein. | 0.692 |
| TOP1 | SUMO1 | ENSNLEP00000007880 | ENSNLEP00000046412 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Small ubiquitin-related modifier. | 0.595 |
