STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.999
CTNND1
Catenin delta 1.
    
 0.999
KLRG1
C-type lectin domain-containing protein.
    
 0.997
JUP
Junction plakoglobin.
   
 0.997
CTNNA1
Catenin alpha 1.
    
 0.994
EGFR
Receptor protein-tyrosine kinase.
   
 
 0.979
CTNNA3
Catenin alpha 3.
    
 0.974
ENSNLEP00000026334
Uncharacterized protein.
    
 
 0.962
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.945
ENSNLEP00000040381
Uncharacterized protein.
    
 0.942
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.