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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHIPHedgehog interacting protein. (700 aa)    
Predicted Functional Partners:
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.992
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.975
IHH
Indian hedgehog signaling molecule.
    
 0.909
PTCH1
Patched 1.
    
 
 0.771
USP38
Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family.
      
 0.700
GLI1
GLI family zinc finger 1.
      
 0.687
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
    
 
 0.684
G1RLD0_NOMLE
Uncharacterized protein.
      
 0.677
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
      
 0.677
FAM13A
Family with sequence similarity 13 member A.
    
 
 0.672
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.