| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMA1 | KITLG | ENSNLEP00000018867 | ENSNLEP00000006667 | Chymase 1; Belongs to the peptidase S1 family. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.882 |
| CMA1 | MMP9 | ENSNLEP00000018867 | ENSNLEP00000008366 | Chymase 1; Belongs to the peptidase S1 family. | Matrix metallopeptidase 9. | 0.455 |
| CSF1R | KITLG | ENSNLEP00000012479 | ENSNLEP00000006667 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.988 |
| EGFR | FLT3 | ENSNLEP00000035792 | ENSNLEP00000000457 | Receptor protein-tyrosine kinase. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.475 |
| EGFR | INSR | ENSNLEP00000035792 | ENSNLEP00000000477 | Receptor protein-tyrosine kinase. | Insulin receptor. | 0.535 |
| EGFR | KDR | ENSNLEP00000035792 | ENSNLEP00000044105 | Receptor protein-tyrosine kinase. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.486 |
| EGFR | KITLG | ENSNLEP00000035792 | ENSNLEP00000006667 | Receptor protein-tyrosine kinase. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.917 |
| EGFR | MMP9 | ENSNLEP00000035792 | ENSNLEP00000008366 | Receptor protein-tyrosine kinase. | Matrix metallopeptidase 9. | 0.507 |
| EGFR | PDGFRA | ENSNLEP00000035792 | ENSNLEP00000010082 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.975 |
| EGFR | PDGFRB | ENSNLEP00000035792 | ENSNLEP00000012499 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.978 |
| FLT3 | EGFR | ENSNLEP00000000457 | ENSNLEP00000035792 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Receptor protein-tyrosine kinase. | 0.475 |
| FLT3 | KITLG | ENSNLEP00000000457 | ENSNLEP00000006667 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.905 |
| FLT3 | PDGFRB | ENSNLEP00000000457 | ENSNLEP00000012499 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.921 |
| INSR | EGFR | ENSNLEP00000000477 | ENSNLEP00000035792 | Insulin receptor. | Receptor protein-tyrosine kinase. | 0.535 |
| INSR | KITLG | ENSNLEP00000000477 | ENSNLEP00000006667 | Insulin receptor. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.909 |
| KDR | EGFR | ENSNLEP00000044105 | ENSNLEP00000035792 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Receptor protein-tyrosine kinase. | 0.486 |
| KDR | KITLG | ENSNLEP00000044105 | ENSNLEP00000006667 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.881 |
| KDR | MMP9 | ENSNLEP00000044105 | ENSNLEP00000008366 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Matrix metallopeptidase 9. | 0.545 |
| KDR | PDGFRB | ENSNLEP00000044105 | ENSNLEP00000012499 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.704 |
| KIT | KITLG | ENSNLEP00000010174 | ENSNLEP00000006667 | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.999 |
