| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GHRHR | PTH | ENSNLEP00000018470 | ENSNLEP00000021470 | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.463 |
| GHRHR | PTHLH | ENSNLEP00000018470 | ENSNLEP00000006750 | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. | Parathyroid hormone like hormone. | 0.570 |
| IHH | PTH | ENSNLEP00000011023 | ENSNLEP00000021470 | Indian hedgehog signaling molecule. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.408 |
| IHH | PTH1R | ENSNLEP00000011023 | ENSNLEP00000007541 | Indian hedgehog signaling molecule. | Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.477 |
| IHH | PTHLH | ENSNLEP00000011023 | ENSNLEP00000006750 | Indian hedgehog signaling molecule. | Parathyroid hormone like hormone. | 0.701 |
| KPNB1 | PTHLH | ENSNLEP00000001948 | ENSNLEP00000006750 | Karyopherin subunit beta 1. | Parathyroid hormone like hormone. | 0.580 |
| LEP | PTH | ENSNLEP00000014938 | ENSNLEP00000021470 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.605 |
| LEP | PTHLH | ENSNLEP00000014938 | ENSNLEP00000006750 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Parathyroid hormone like hormone. | 0.547 |
| LEP | SOST | ENSNLEP00000014938 | ENSNLEP00000006914 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Sclerostin. | 0.571 |
| PTH | GHRHR | ENSNLEP00000021470 | ENSNLEP00000018470 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. | 0.463 |
| PTH | IHH | ENSNLEP00000021470 | ENSNLEP00000011023 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Indian hedgehog signaling molecule. | 0.408 |
| PTH | LEP | ENSNLEP00000021470 | ENSNLEP00000014938 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.605 |
| PTH | PTH1R | ENSNLEP00000021470 | ENSNLEP00000007541 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.997 |
| PTH | PTH2R | ENSNLEP00000021470 | ENSNLEP00000031587 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.994 |
| PTH | PTHLH | ENSNLEP00000021470 | ENSNLEP00000006750 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Parathyroid hormone like hormone. | 0.765 |
| PTH | SCTR | ENSNLEP00000021470 | ENSNLEP00000012559 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Secretin receptor; Belongs to the G-protein coupled receptor 2 family. | 0.605 |
| PTH | SOST | ENSNLEP00000021470 | ENSNLEP00000006914 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Sclerostin. | 0.635 |
| PTH1R | IHH | ENSNLEP00000007541 | ENSNLEP00000011023 | Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. | Indian hedgehog signaling molecule. | 0.477 |
| PTH1R | PTH | ENSNLEP00000007541 | ENSNLEP00000021470 | Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.997 |
| PTH1R | PTH2R | ENSNLEP00000007541 | ENSNLEP00000031587 | Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. | Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.913 |
