USP13 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG6	ENSNLEP00000034619	ENSNLEP00000007502	ENSNLEP00000034619	BCL2 associated athanogene 6.	Ubiquitin-like domain-containing protein.	0.559
BAG6	USP13	ENSNLEP00000007502	ENSNLEP00000007105	BCL2 associated athanogene 6.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.809
BECN1	ENSNLEP00000034619	ENSNLEP00000014406	ENSNLEP00000034619	Beclin 1.	Ubiquitin-like domain-containing protein.	0.411
BECN1	MCL1	ENSNLEP00000014406	ENSNLEP00000012087	Beclin 1.	MCL1 apoptosis regulator, BCL2 family member.	0.687
BECN1	USP10	ENSNLEP00000014406	ENSNLEP00000046179	Beclin 1.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.628
BECN1	USP13	ENSNLEP00000014406	ENSNLEP00000007105	Beclin 1.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.957
ENSNLEP00000025290	ENSNLEP00000034619	ENSNLEP00000025290	ENSNLEP00000034619	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.839
ENSNLEP00000025290	USP13	ENSNLEP00000025290	ENSNLEP00000007105	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.804
ENSNLEP00000034619	BAG6	ENSNLEP00000034619	ENSNLEP00000007502	Ubiquitin-like domain-containing protein.	BCL2 associated athanogene 6.	0.559
ENSNLEP00000034619	BECN1	ENSNLEP00000034619	ENSNLEP00000014406	Ubiquitin-like domain-containing protein.	Beclin 1.	0.411
ENSNLEP00000034619	ENSNLEP00000025290	ENSNLEP00000034619	ENSNLEP00000025290	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.839
ENSNLEP00000034619	PTEN	ENSNLEP00000034619	ENSNLEP00000014741	Ubiquitin-like domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.816
ENSNLEP00000034619	SIAH1	ENSNLEP00000034619	ENSNLEP00000031204	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.400
ENSNLEP00000034619	SIAH2	ENSNLEP00000034619	ENSNLEP00000004055	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.432
ENSNLEP00000034619	USP10	ENSNLEP00000034619	ENSNLEP00000046179	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.864
ENSNLEP00000034619	USP13	ENSNLEP00000034619	ENSNLEP00000007105	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.925
MCL1	BECN1	ENSNLEP00000012087	ENSNLEP00000014406	MCL1 apoptosis regulator, BCL2 family member.	Beclin 1.	0.687
MCL1	USP13	ENSNLEP00000012087	ENSNLEP00000007105	MCL1 apoptosis regulator, BCL2 family member.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.846
PTEN	ENSNLEP00000034619	ENSNLEP00000014741	ENSNLEP00000034619	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin-like domain-containing protein.	0.816
PTEN	USP10	ENSNLEP00000014741	ENSNLEP00000046179	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.818

page 1 of 3

Server load: low (18%) [HD]

Share

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About