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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC14Tetratricopeptide repeat domain 14. (772 aa)    
Predicted Functional Partners:
PNISR
PNN interacting serine and arginine rich protein.
   
   0.773
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
   
  
 0.748
CLDN18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.713
FXR1
FMR1 autosomal homolog 1.
   
 
 0.675
ZFC3H1
Zinc finger C3H1-type containing.
   
   0.594
ESS2
Ess-2 splicing factor homolog.
   
 
 0.579
SF3B1
Splicing factor 3b subunit 1.
   
  
 0.527
RNPC3
RNA binding region (RNP1, RRM) containing 3.
   
   0.488
ENSNLEP00000041142
Uncharacterized protein.
   
   0.488
PRPF39
Pre-mRNA processing factor 39.
   
    0.446
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.