KLHL6 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KLHL6

BTB domain-containing protein. (614 aa)

Predicted Functional Partners:

PTPN14

0.715

RC3H2

0.687

CUL3

0.672

BBS1

0.591

BBS9

0.585

BBS7

0.563

TTC8

0.540

BBS4

0.538

LOC100593615

0.538

CUL1

0.516

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS1	BBS4	ENSNLEP00000036650	ENSNLEP00000017129	Uncharacterized protein.	Bardet-Biedl syndrome 4.	0.990
BBS1	BBS7	ENSNLEP00000036650	ENSNLEP00000011397	Uncharacterized protein.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS1	BBS9	ENSNLEP00000036650	ENSNLEP00000035803	Uncharacterized protein.	Bardet-Biedl syndrome 9.	0.999
BBS1	KLHL6	ENSNLEP00000036650	ENSNLEP00000007342	Uncharacterized protein.	BTB domain-containing protein.	0.591
BBS1	LOC100593615	ENSNLEP00000036650	ENSNLEP00000036166	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.986
BBS1	TTC8	ENSNLEP00000036650	ENSNLEP00000039635	Uncharacterized protein.	Tetratricopeptide repeat domain 8.	0.998
BBS4	BBS1	ENSNLEP00000017129	ENSNLEP00000036650	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.990
BBS4	BBS7	ENSNLEP00000017129	ENSNLEP00000011397	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.978
BBS4	BBS9	ENSNLEP00000017129	ENSNLEP00000035803	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 9.	0.989
BBS4	KLHL6	ENSNLEP00000017129	ENSNLEP00000007342	Bardet-Biedl syndrome 4.	BTB domain-containing protein.	0.538
BBS4	TTC8	ENSNLEP00000017129	ENSNLEP00000039635	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.988
BBS7	BBS1	ENSNLEP00000011397	ENSNLEP00000036650	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Uncharacterized protein.	0.999
BBS7	BBS4	ENSNLEP00000011397	ENSNLEP00000017129	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 4.	0.978
BBS7	BBS9	ENSNLEP00000011397	ENSNLEP00000035803	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 9.	0.999
BBS7	KLHL6	ENSNLEP00000011397	ENSNLEP00000007342	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	BTB domain-containing protein.	0.563
BBS7	LOC100593615	ENSNLEP00000011397	ENSNLEP00000036166	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	TPR_REGION domain-containing protein.	0.967
BBS7	TTC8	ENSNLEP00000011397	ENSNLEP00000039635	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Tetratricopeptide repeat domain 8.	0.998
BBS9	BBS1	ENSNLEP00000035803	ENSNLEP00000036650	Bardet-Biedl syndrome 9.	Uncharacterized protein.	0.999
BBS9	BBS4	ENSNLEP00000035803	ENSNLEP00000017129	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 4.	0.989
BBS9	BBS7	ENSNLEP00000035803	ENSNLEP00000011397	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999

page 1 of 3

Server load: medium (44%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About