| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHMP4B | HGS | ENSNLEP00000012220 | ENSNLEP00000016808 | Charged multivesicular body protein 4B. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.688 |
| CHMP4B | IST1 | ENSNLEP00000012220 | ENSNLEP00000025984 | Charged multivesicular body protein 4B. | IST1 factor associated with ESCRT-III. | 0.930 |
| CHMP4B | PTPN23 | ENSNLEP00000012220 | ENSNLEP00000007674 | Charged multivesicular body protein 4B. | Protein tyrosine phosphatase non-receptor type 23. | 0.838 |
| CHMP4B | VPS4B | ENSNLEP00000012220 | ENSNLEP00000044753 | Charged multivesicular body protein 4B. | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. | 0.984 |
| GRAP2 | GRB2 | ENSNLEP00000036468 | ENSNLEP00000040743 | GRB2 related adaptor protein 2. | Growth factor receptor bound protein 2. | 0.712 |
| GRAP2 | PTPN23 | ENSNLEP00000036468 | ENSNLEP00000007674 | GRB2 related adaptor protein 2. | Protein tyrosine phosphatase non-receptor type 23. | 0.799 |
| GRAP2 | STAM2 | ENSNLEP00000036468 | ENSNLEP00000013744 | GRB2 related adaptor protein 2. | Signal transducing adaptor molecule 2. | 0.430 |
| GRB2 | GRAP2 | ENSNLEP00000040743 | ENSNLEP00000036468 | Growth factor receptor bound protein 2. | GRB2 related adaptor protein 2. | 0.712 |
| GRB2 | HGS | ENSNLEP00000040743 | ENSNLEP00000016808 | Growth factor receptor bound protein 2. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.582 |
| GRB2 | PTPN23 | ENSNLEP00000040743 | ENSNLEP00000007674 | Growth factor receptor bound protein 2. | Protein tyrosine phosphatase non-receptor type 23. | 0.818 |
| GRB2 | STAM2 | ENSNLEP00000040743 | ENSNLEP00000013744 | Growth factor receptor bound protein 2. | Signal transducing adaptor molecule 2. | 0.677 |
| HGS | CHMP4B | ENSNLEP00000016808 | ENSNLEP00000012220 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Charged multivesicular body protein 4B. | 0.688 |
| HGS | GRB2 | ENSNLEP00000016808 | ENSNLEP00000040743 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Growth factor receptor bound protein 2. | 0.582 |
| HGS | IST1 | ENSNLEP00000016808 | ENSNLEP00000025984 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | IST1 factor associated with ESCRT-III. | 0.703 |
| HGS | PTPN23 | ENSNLEP00000016808 | ENSNLEP00000007674 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Protein tyrosine phosphatase non-receptor type 23. | 0.845 |
| HGS | STAM2 | ENSNLEP00000016808 | ENSNLEP00000013744 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule 2. | 0.999 |
| HGS | VPS4B | ENSNLEP00000016808 | ENSNLEP00000044753 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. | 0.680 |
| IST1 | CHMP4B | ENSNLEP00000025984 | ENSNLEP00000012220 | IST1 factor associated with ESCRT-III. | Charged multivesicular body protein 4B. | 0.930 |
| IST1 | HGS | ENSNLEP00000025984 | ENSNLEP00000016808 | IST1 factor associated with ESCRT-III. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.703 |
| IST1 | PTPN23 | ENSNLEP00000025984 | ENSNLEP00000007674 | IST1 factor associated with ESCRT-III. | Protein tyrosine phosphatase non-receptor type 23. | 0.734 |
