IMPACT protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IMPACT

Impact RWD domain protein. (320 aa)

Predicted Functional Partners:

GRHPR

0.776

ENSNLEP00000030795

0.757

CMPK2

0.757

ENSNLEP00000030516

0.753

ENSNLEP00000024799

0.702

GCSH

0.702

CTBP2

0.666

PHGDH

0.666

CTBP1

0.666

ITPA

0.613

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMPK2	ENSNLEP00000030516	ENSNLEP00000046149	ENSNLEP00000030516	Thymidylate_kin domain-containing protein.	Thymidine kinase.	0.852
CMPK2	ENSNLEP00000030795	ENSNLEP00000046149	ENSNLEP00000030795	Thymidylate_kin domain-containing protein.	Thymidylate_kin domain-containing protein.	0.693
CMPK2	IMPACT	ENSNLEP00000046149	ENSNLEP00000008007	Thymidylate_kin domain-containing protein.	Impact RWD domain protein.	0.757
CTBP1	CTBP2	ENSNLEP00000035151	ENSNLEP00000000712	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.979
CTBP1	ENSNLEP00000024799	ENSNLEP00000035151	ENSNLEP00000024799	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.586
CTBP1	GCSH	ENSNLEP00000035151	ENSNLEP00000031181	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.586
CTBP1	IMPACT	ENSNLEP00000035151	ENSNLEP00000008007	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Impact RWD domain protein.	0.666
CTBP2	CTBP1	ENSNLEP00000000712	ENSNLEP00000035151	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.979
CTBP2	ENSNLEP00000024799	ENSNLEP00000000712	ENSNLEP00000024799	C-terminal binding protein 2.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.586
CTBP2	GCSH	ENSNLEP00000000712	ENSNLEP00000031181	C-terminal binding protein 2.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.586
CTBP2	IMPACT	ENSNLEP00000000712	ENSNLEP00000008007	C-terminal binding protein 2.	Impact RWD domain protein.	0.666
ENSNLEP00000024799	CTBP1	ENSNLEP00000024799	ENSNLEP00000035151	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.586
ENSNLEP00000024799	CTBP2	ENSNLEP00000024799	ENSNLEP00000000712	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	C-terminal binding protein 2.	0.586
ENSNLEP00000024799	GRHPR	ENSNLEP00000024799	ENSNLEP00000026425	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.786
ENSNLEP00000024799	IMPACT	ENSNLEP00000024799	ENSNLEP00000008007	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	Impact RWD domain protein.	0.702
ENSNLEP00000024799	PHGDH	ENSNLEP00000024799	ENSNLEP00000006595	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.613
ENSNLEP00000030516	CMPK2	ENSNLEP00000030516	ENSNLEP00000046149	Thymidine kinase.	Thymidylate_kin domain-containing protein.	0.852
ENSNLEP00000030516	ENSNLEP00000030795	ENSNLEP00000030516	ENSNLEP00000030795	Thymidine kinase.	Thymidylate_kin domain-containing protein.	0.891
ENSNLEP00000030516	IMPACT	ENSNLEP00000030516	ENSNLEP00000008007	Thymidine kinase.	Impact RWD domain protein.	0.753
ENSNLEP00000030795	CMPK2	ENSNLEP00000030795	ENSNLEP00000046149	Thymidylate_kin domain-containing protein.	Thymidylate_kin domain-containing protein.	0.693

page 1 of 3

Server load: low (32%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About