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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)    
Predicted Functional Partners:
ENSNLEP00000034619
Ubiquitin-like domain-containing protein.
    
 0.749
DVL1
Dishevelled segment polarity protein 1.
    
 0.681
SMAD4
Mothers against decapentaplegic homolog.
   
 0.658
SMAD7
Mothers against decapentaplegic homolog.
    
 0.634
SMAD6
Mothers against decapentaplegic homolog.
    
 0.634
ENSNLEP00000037583
Ubiquitin-like domain-containing protein.
    
 0.631
ENSNLEP00000038579
Ubiquitin-like domain-containing protein.
    
 0.631
AMOTL1
Angiomotin like 1.
    
 0.601
ITSN2
Intersectin 2.
   
  0.589
RPS27A-2
Ubiquitin-like domain-containing protein.
    
 0.588
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.