Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TYMSThymidylat_synt domain-containing protein. (173 aa)    
Predicted Functional Partners:
DHFR
DHFR domain-containing protein.
 
 
 0.995
ENSNLEP00000030516
Thymidine kinase.
  
 
 0.994
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.987
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.986
DCTD
dCMP deaminase.
  
 
 0.984
ENSNLEP00000030795
Thymidylate_kin domain-containing protein.
  
 
 0.983
DUT
Deoxyuridine triphosphatase.
  
 0.982
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.978
TK2
Thymidine kinase 2.
  
 
 0.975
MTHFD2
Uncharacterized protein.
  
 
 0.967
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: medium (44%) [HD]