STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO2Shugoshin 2. (1184 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.948
SGO1
Shugoshin 1.
  
  
 0.926
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.842
REC8
REC8 meiotic recombination protein.
     
 0.838
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.832
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.806
RAD21
RAD21 cohesin complex component.
     
 0.789
CDCA8
Cell division cycle associated 8.
   
 
 0.786
CDC20
Cell division cycle 20.
   
 
 0.783
ENSNLEP00000028618
WD_REPEATS_REGION domain-containing protein.
   
 
 0.783
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.