STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1628 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
    
 0.948
ENSNLEP00000024537
A20-type domain-containing protein.
   
 0.930
RABGEF1
RAB guanine nucleotide exchange factor 1.
   
 0.930
NEK1
NIMA related kinase 1.
   
 0.884
CFAP410
LRRcap domain-containing protein.
   
 
 0.819
GAPVD1
GTPase activating protein and VPS9 domains 1.
   
 0.793
ZFAND4
Zinc finger AN1-type containing 4.
    
 0.719
RANBP2
RAN binding protein 2.
   
 0.700
SOD1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
    
 
 0.687
SETX
Senataxin.
      
 0.687
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.