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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP3Poly [ADP-ribose] polymerase. (522 aa)    
Predicted Functional Partners:
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.826
APLF
Aprataxin and PNKP like factor.
    
 
 0.764
HPF1
Histone PARylation factor 1.
    
 
 0.695
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.658
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 
 0.652
CHD1L
Chromodomain helicase DNA binding protein 1 like.
   
 0.636
XPA
XPA, DNA damage recognition and repair factor.
     
 0.608
SMAD4
Mothers against decapentaplegic homolog.
     
 0.604
XRCC6
X-ray repair cross complementing 6.
   
 
 0.603
LOC100580673
Ku domain-containing protein.
   
 
 0.603
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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