STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (425 aa)    
Predicted Functional Partners:
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
     
0.781
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.774
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
     
 0.743
ENSNLEP00000044067
Uncharacterized protein.
     
 0.742
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.706
CASP1
Caspase 1; Belongs to the peptidase C14A family.
    
 
 0.637
NLRP1
NLR family pyrin domain containing 1.
     
 0.617
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 
 0.613
ENSNLEP00000036074
Uncharacterized protein.
      
 0.607
KCNS1
Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family.
      
 0.598
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.