STRINGSTRING
GRIA4 protein (Nomascus leucogenys) - STRING interaction network
"GRIA4" - Glutamate receptor, ionotropic, AMPA 4 in Nomascus leucogenys
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIA4Glutamate receptor, ionotropic, AMPA 4 (902 aa)    
Predicted Functional Partners:
GRIA2
Glutamate receptor, ionotropic, AMPA 2 (883 aa)
     
 
0.849
KIF5C
Kinesin-like protein; Kinesin family member 5C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (777 aa)
     
  0.833
KIF5B
Kinesin-like protein; Kinesin family member 5B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (963 aa)
     
  0.828
PRKACA
Protein kinase, cAMP-dependent, catalytic, alpha; Belongs to the protein kinase superfamily (249 aa)
     
  0.826
CACNG2
Multifunctional fusion protein; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (323 aa)
     
 
  0.826
PRKACB
Protein kinase, cAMP-dependent, catalytic, beta (351 aa)
     
  0.821
DLG1
Discs, large homolog 1 (Drosophila); Belongs to the MAGUK family (924 aa)
     
 
  0.778
DLG4
Discs, large homolog 4 (Drosophila); Belongs to the MAGUK family (767 aa)
     
 
  0.729
DLG2
Discs, large homolog 2 (Drosophila) (909 aa)
     
 
  0.667
DLG3
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family (849 aa)
     
 
  0.637
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (4%) [ZH]