Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANKK1Ankyrin repeat and kinase domain containing 1. (733 aa)    
Predicted Functional Partners:
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
   
 0.717
TTC12
Tetratricopeptide repeat domain 12.
    
 
 0.700
TPH2
Tryptophan hydroxylase 2.
      
 0.660
LRRC51
Uncharacterized protein.
      
 0.607
WDR38
WD repeat domain 38.
   
 0.585
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.579
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
      
 0.576
INPP1
Inositol polyphosphate-1-phosphatase.
      
 0.551
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.551
MROH2B
Maestro heat like repeat family member 2B.
   
  
 0.543
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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