TMPRSS5 protein (Nomascus leucogenys) - STRING interaction network

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TMPRSS5

Transmembrane serine protease 5; Belongs to the peptidase S1 family. (428 aa)

Predicted Functional Partners:

MST1R

0.517

MET

0.517

CTRL

0.477

CLEC2A

0.426

SPINT2

0.417

LYG2

0.409

TMCO5A

0.400

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC2A	LYG2	ENSNLEP00000003714	ENSNLEP00000002604	C-type lectin domain family 2 member A.	Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family.	0.466
CLEC2A	TMPRSS5	ENSNLEP00000003714	ENSNLEP00000008919	C-type lectin domain family 2 member A.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.426
CTRL	MET	ENSNLEP00000006078	ENSNLEP00000024614	Chymotrypsin like; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.531
CTRL	MST1R	ENSNLEP00000006078	ENSNLEP00000008444	Chymotrypsin like; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.517
CTRL	TMPRSS5	ENSNLEP00000006078	ENSNLEP00000008919	Chymotrypsin like; Belongs to the peptidase S1 family.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.477
LYG2	CLEC2A	ENSNLEP00000002604	ENSNLEP00000003714	Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family.	C-type lectin domain family 2 member A.	0.466
LYG2	TMPRSS5	ENSNLEP00000002604	ENSNLEP00000008919	Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.409
MET	CTRL	ENSNLEP00000024614	ENSNLEP00000006078	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Chymotrypsin like; Belongs to the peptidase S1 family.	0.531
MET	MST1R	ENSNLEP00000024614	ENSNLEP00000008444	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.737
MET	TMPRSS5	ENSNLEP00000024614	ENSNLEP00000008919	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.517
MST1R	CTRL	ENSNLEP00000008444	ENSNLEP00000006078	Macrophage stimulating 1 receptor.	Chymotrypsin like; Belongs to the peptidase S1 family.	0.517
MST1R	MET	ENSNLEP00000008444	ENSNLEP00000024614	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.737
MST1R	TMPRSS5	ENSNLEP00000008444	ENSNLEP00000008919	Macrophage stimulating 1 receptor.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.517
SPINT2	TMPRSS5	ENSNLEP00000020563	ENSNLEP00000008919	Serine peptidase inhibitor, Kunitz type 2.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.417
TMCO5A	TMPRSS5	ENSNLEP00000045017	ENSNLEP00000008919	Transmembrane and coiled-coil domains 5A.	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	0.400
TMPRSS5	CLEC2A	ENSNLEP00000008919	ENSNLEP00000003714	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	C-type lectin domain family 2 member A.	0.426
TMPRSS5	CTRL	ENSNLEP00000008919	ENSNLEP00000006078	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	Chymotrypsin like; Belongs to the peptidase S1 family.	0.477
TMPRSS5	LYG2	ENSNLEP00000008919	ENSNLEP00000002604	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family.	0.409
TMPRSS5	MET	ENSNLEP00000008919	ENSNLEP00000024614	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.517
TMPRSS5	MST1R	ENSNLEP00000008919	ENSNLEP00000008444	Transmembrane serine protease 5; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.517

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