DDX6 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	DCP1A	ENSNLEP00000001761	ENSNLEP00000008806	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Decapping mRNA 1A.	0.409
AGO2	DCP2	ENSNLEP00000001761	ENSNLEP00000014121	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Decapping mRNA 2.	0.637
AGO2	DDX6	ENSNLEP00000001761	ENSNLEP00000008992	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.935
AGO2	EDC4	ENSNLEP00000001761	ENSNLEP00000006052	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Enhancer of mRNA decapping 4.	0.573
AGO2	PATL1	ENSNLEP00000001761	ENSNLEP00000015894	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	PAT1 homolog 1, processing body mRNA decay factor.	0.403
DCP1A	AGO2	ENSNLEP00000008806	ENSNLEP00000001761	Decapping mRNA 1A.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.409
DCP1A	DCP1B	ENSNLEP00000008806	ENSNLEP00000003294	Decapping mRNA 1A.	Decapping mRNA 1B.	0.998
DCP1A	DCP2	ENSNLEP00000008806	ENSNLEP00000014121	Decapping mRNA 1A.	Decapping mRNA 2.	0.997
DCP1A	DDX6	ENSNLEP00000008806	ENSNLEP00000008992	Decapping mRNA 1A.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.994
DCP1A	EDC3	ENSNLEP00000008806	ENSNLEP00000017729	Decapping mRNA 1A.	Enhancer of mRNA decapping 3.	0.997
DCP1A	EDC4	ENSNLEP00000008806	ENSNLEP00000006052	Decapping mRNA 1A.	Enhancer of mRNA decapping 4.	0.997
DCP1A	LSM1	ENSNLEP00000008806	ENSNLEP00000049037	Decapping mRNA 1A.	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.	0.794
DCP1A	LSM14B	ENSNLEP00000008806	ENSNLEP00000019108	Decapping mRNA 1A.	LSM family member 14B.	0.537
DCP1A	LSM4	ENSNLEP00000008806	ENSNLEP00000038274	Decapping mRNA 1A.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.868
DCP1A	PATL1	ENSNLEP00000008806	ENSNLEP00000015894	Decapping mRNA 1A.	PAT1 homolog 1, processing body mRNA decay factor.	0.970
DCP1B	DCP1A	ENSNLEP00000003294	ENSNLEP00000008806	Decapping mRNA 1B.	Decapping mRNA 1A.	0.998
DCP1B	DCP2	ENSNLEP00000003294	ENSNLEP00000014121	Decapping mRNA 1B.	Decapping mRNA 2.	0.994
DCP1B	DDX6	ENSNLEP00000003294	ENSNLEP00000008992	Decapping mRNA 1B.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.985
DCP1B	EDC3	ENSNLEP00000003294	ENSNLEP00000017729	Decapping mRNA 1B.	Enhancer of mRNA decapping 3.	0.992
DCP1B	EDC4	ENSNLEP00000003294	ENSNLEP00000006052	Decapping mRNA 1B.	Enhancer of mRNA decapping 4.	0.986

page 1 of 5

Server load: low (14%) [HD]

Share

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About