| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASAP3 | PDZD3 | ENSNLEP00000010421 | ENSNLEP00000009015 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. | PDZ domain containing 3. | 0.585 |
| CASK | PDZD3 | ENSNLEP00000002678 | ENSNLEP00000009015 | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | PDZ domain containing 3. | 0.515 |
| CFTR | GUCA2A | ENSNLEP00000014239 | ENSNLEP00000014915 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Guanylate cyclase activator 2A. | 0.520 |
| CFTR | GUCA2B | ENSNLEP00000014239 | ENSNLEP00000014912 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Guanylate cyclase activator 2B. | 0.490 |
| CFTR | GUCY2C | ENSNLEP00000014239 | ENSNLEP00000004736 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Guanylate cyclase. | 0.543 |
| CFTR | PDZD3 | ENSNLEP00000014239 | ENSNLEP00000009015 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | PDZ domain containing 3. | 0.512 |
| GRHPR | PDZD3 | ENSNLEP00000026425 | ENSNLEP00000009015 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | PDZ domain containing 3. | 0.500 |
| GRHPR | WDR76 | ENSNLEP00000026425 | ENSNLEP00000006664 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. | 0.407 |
| GUCA2A | CFTR | ENSNLEP00000014915 | ENSNLEP00000014239 | Guanylate cyclase activator 2A. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.520 |
| GUCA2A | GUCA2B | ENSNLEP00000014915 | ENSNLEP00000014912 | Guanylate cyclase activator 2A. | Guanylate cyclase activator 2B. | 0.958 |
| GUCA2A | GUCY2C | ENSNLEP00000014915 | ENSNLEP00000004736 | Guanylate cyclase activator 2A. | Guanylate cyclase. | 0.987 |
| GUCA2A | PDZD3 | ENSNLEP00000014915 | ENSNLEP00000009015 | Guanylate cyclase activator 2A. | PDZ domain containing 3. | 0.533 |
| GUCA2B | CFTR | ENSNLEP00000014912 | ENSNLEP00000014239 | Guanylate cyclase activator 2B. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.490 |
| GUCA2B | GUCA2A | ENSNLEP00000014912 | ENSNLEP00000014915 | Guanylate cyclase activator 2B. | Guanylate cyclase activator 2A. | 0.958 |
| GUCA2B | GUCY2C | ENSNLEP00000014912 | ENSNLEP00000004736 | Guanylate cyclase activator 2B. | Guanylate cyclase. | 0.997 |
| GUCA2B | PDZD3 | ENSNLEP00000014912 | ENSNLEP00000009015 | Guanylate cyclase activator 2B. | PDZ domain containing 3. | 0.558 |
| GUCY2C | CFTR | ENSNLEP00000004736 | ENSNLEP00000014239 | Guanylate cyclase. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.543 |
| GUCY2C | GUCA2A | ENSNLEP00000004736 | ENSNLEP00000014915 | Guanylate cyclase. | Guanylate cyclase activator 2A. | 0.987 |
| GUCY2C | GUCA2B | ENSNLEP00000004736 | ENSNLEP00000014912 | Guanylate cyclase. | Guanylate cyclase activator 2B. | 0.997 |
| GUCY2C | PDZD3 | ENSNLEP00000004736 | ENSNLEP00000009015 | Guanylate cyclase. | PDZ domain containing 3. | 0.644 |
