| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BST1 | CD38 | ENSNLEP00000035736 | ENSNLEP00000027940 | Bone marrow stromal cell antigen 1. | CD38 molecule. | 0.908 |
| BST1 | NADSYN1 | ENSNLEP00000035736 | ENSNLEP00000013084 | Bone marrow stromal cell antigen 1. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.911 |
| BST1 | NAMPT | ENSNLEP00000035736 | ENSNLEP00000010796 | Bone marrow stromal cell antigen 1. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.932 |
| BST1 | SARM1 | ENSNLEP00000035736 | ENSNLEP00000002578 | Bone marrow stromal cell antigen 1. | Sterile alpha and TIR motif containing 1. | 0.947 |
| BST1 | SIRT1 | ENSNLEP00000035736 | ENSNLEP00000014593 | Bone marrow stromal cell antigen 1. | Sirtuin 1. | 0.913 |
| BST1 | SIRT2 | ENSNLEP00000035736 | ENSNLEP00000017842 | Bone marrow stromal cell antigen 1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.909 |
| BST1 | SIRT3 | ENSNLEP00000035736 | ENSNLEP00000018956 | Bone marrow stromal cell antigen 1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.912 |
| BST1 | SIRT4 | ENSNLEP00000035736 | ENSNLEP00000018942 | Bone marrow stromal cell antigen 1. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.909 |
| BST1 | SIRT5 | ENSNLEP00000035736 | ENSNLEP00000026965 | Bone marrow stromal cell antigen 1. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.911 |
| BST1 | SIRT7 | ENSNLEP00000035736 | ENSNLEP00000009137 | Bone marrow stromal cell antigen 1. | Sirtuin 7. | 0.921 |
| CD38 | BST1 | ENSNLEP00000027940 | ENSNLEP00000035736 | CD38 molecule. | Bone marrow stromal cell antigen 1. | 0.908 |
| CD38 | NADSYN1 | ENSNLEP00000027940 | ENSNLEP00000013084 | CD38 molecule. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.904 |
| CD38 | NAMPT | ENSNLEP00000027940 | ENSNLEP00000010796 | CD38 molecule. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.934 |
| CD38 | SARM1 | ENSNLEP00000027940 | ENSNLEP00000002578 | CD38 molecule. | Sterile alpha and TIR motif containing 1. | 0.936 |
| CD38 | SIRT1 | ENSNLEP00000027940 | ENSNLEP00000014593 | CD38 molecule. | Sirtuin 1. | 0.926 |
| CD38 | SIRT2 | ENSNLEP00000027940 | ENSNLEP00000017842 | CD38 molecule. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.911 |
| CD38 | SIRT3 | ENSNLEP00000027940 | ENSNLEP00000018956 | CD38 molecule. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.921 |
| CD38 | SIRT4 | ENSNLEP00000027940 | ENSNLEP00000018942 | CD38 molecule. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.907 |
| CD38 | SIRT5 | ENSNLEP00000027940 | ENSNLEP00000026965 | CD38 molecule. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.911 |
| CD38 | SIRT7 | ENSNLEP00000027940 | ENSNLEP00000009137 | CD38 molecule. | Sirtuin 7. | 0.942 |
