| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCLRE1A | EME1 | ENSNLEP00000019618 | ENSNLEP00000011035 | DNA cross-link repair 1A. | Essential meiotic structure-specific endonuclease 1. | 0.857 |
| DCLRE1A | FAN1 | ENSNLEP00000019618 | ENSNLEP00000009162 | DNA cross-link repair 1A. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.843 |
| DCLRE1A | FANCD2 | ENSNLEP00000019618 | ENSNLEP00000033029 | DNA cross-link repair 1A. | FA complementation group D2. | 0.863 |
| DCLRE1A | FANCI | ENSNLEP00000019618 | ENSNLEP00000014138 | DNA cross-link repair 1A. | FA complementation group I. | 0.815 |
| DCLRE1A | FANCM | ENSNLEP00000019618 | ENSNLEP00000048241 | DNA cross-link repair 1A. | FA complementation group M. | 0.808 |
| DCLRE1A | SLX1A | ENSNLEP00000019618 | ENSNLEP00000001190 | DNA cross-link repair 1A. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.765 |
| EME1 | DCLRE1A | ENSNLEP00000011035 | ENSNLEP00000019618 | Essential meiotic structure-specific endonuclease 1. | DNA cross-link repair 1A. | 0.857 |
| EME1 | FAN1 | ENSNLEP00000011035 | ENSNLEP00000009162 | Essential meiotic structure-specific endonuclease 1. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.817 |
| EME1 | FANCD2 | ENSNLEP00000011035 | ENSNLEP00000033029 | Essential meiotic structure-specific endonuclease 1. | FA complementation group D2. | 0.869 |
| EME1 | FANCI | ENSNLEP00000011035 | ENSNLEP00000014138 | Essential meiotic structure-specific endonuclease 1. | FA complementation group I. | 0.849 |
| EME1 | FANCM | ENSNLEP00000011035 | ENSNLEP00000048241 | Essential meiotic structure-specific endonuclease 1. | FA complementation group M. | 0.829 |
| EME1 | MLH1 | ENSNLEP00000011035 | ENSNLEP00000006040 | Essential meiotic structure-specific endonuclease 1. | MutL homolog 1. | 0.409 |
| EME1 | SLX1A | ENSNLEP00000011035 | ENSNLEP00000001190 | Essential meiotic structure-specific endonuclease 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.902 |
| FAN1 | DCLRE1A | ENSNLEP00000009162 | ENSNLEP00000019618 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | DNA cross-link repair 1A. | 0.843 |
| FAN1 | EME1 | ENSNLEP00000009162 | ENSNLEP00000011035 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Essential meiotic structure-specific endonuclease 1. | 0.817 |
| FAN1 | FANCD2 | ENSNLEP00000009162 | ENSNLEP00000033029 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group D2. | 0.998 |
| FAN1 | FANCI | ENSNLEP00000009162 | ENSNLEP00000014138 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group I. | 0.908 |
| FAN1 | FANCM | ENSNLEP00000009162 | ENSNLEP00000048241 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group M. | 0.832 |
| FAN1 | G1QJN0_NOMLE | ENSNLEP00000009162 | ENSNLEP00000001125 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Uncharacterized protein. | 0.982 |
| FAN1 | LOC100597058 | ENSNLEP00000009162 | ENSNLEP00000026546 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | MutL_C domain-containing protein. | 0.982 |
