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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNE1Cyclin E1; Belongs to the cyclin family. (402 aa)    
Predicted Functional Partners:
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.999
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.999
CDKN1B
Uncharacterized protein.
   
 0.999
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.999
RB1
RB transcriptional corepressor 1.
   
 0.996
RBL2
RB transcriptional corepressor like 2.
   
 0.986
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.986
SKP2
S-phase kinase associated protein 2.
   
 0.986
CDC25A
Cell division cycle 25A.
   
 0.982
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.978
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.