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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNA7Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (358 aa)    
Predicted Functional Partners:
CHRNA6
Cholinergic receptor nicotinic alpha 6 subunit.
  
0.952
CHRNA3
Cholinergic receptor nicotinic alpha 3 subunit.
  
0.947
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
     
 0.916
JAK2
Tyrosine-protein kinase.
    
 0.915
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.908
P2RX6
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.903
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
     
 0.903
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.903
ENSNLEP00000031077
Neur_chan_LBD domain-containing protein.
 
     0.797
SLURP1
Secreted LY6/PLAUR domain containing 1.
    
 0.756
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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