| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AREG | EGF | ENSNLEP00000040124 | ENSNLEP00000020085 | EGF-like domain-containing protein. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.936 |
| AREG | EGFR | ENSNLEP00000040124 | ENSNLEP00000035792 | EGF-like domain-containing protein. | Receptor protein-tyrosine kinase. | 0.997 |
| AREG | ERBB2 | ENSNLEP00000040124 | ENSNLEP00000048945 | EGF-like domain-containing protein. | Receptor protein-tyrosine kinase. | 0.926 |
| AREG | ERBB3 | ENSNLEP00000040124 | ENSNLEP00000047229 | EGF-like domain-containing protein. | Erb-b2 receptor tyrosine kinase 3. | 0.952 |
| AREG | ERBB4 | ENSNLEP00000040124 | ENSNLEP00000008780 | EGF-like domain-containing protein. | Receptor protein-tyrosine kinase. | 0.951 |
| AREG | EREG | ENSNLEP00000040124 | ENSNLEP00000009683 | EGF-like domain-containing protein. | Epiregulin. | 0.936 |
| AREG | HBEGF | ENSNLEP00000040124 | ENSNLEP00000011230 | EGF-like domain-containing protein. | Heparin binding EGF like growth factor. | 0.673 |
| AREG | MET | ENSNLEP00000040124 | ENSNLEP00000024614 | EGF-like domain-containing protein. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.762 |
| AREG | NTRK1 | ENSNLEP00000040124 | ENSNLEP00000047218 | EGF-like domain-containing protein. | Tyrosine-protein kinase receptor. | 0.796 |
| AREG | TGFA | ENSNLEP00000040124 | ENSNLEP00000012418 | EGF-like domain-containing protein. | Transforming growth factor alpha. | 0.815 |
| EGF | AREG | ENSNLEP00000020085 | ENSNLEP00000040124 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | EGF-like domain-containing protein. | 0.936 |
| EGF | EGFR | ENSNLEP00000020085 | ENSNLEP00000035792 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Receptor protein-tyrosine kinase. | 0.999 |
| EGF | ERBB2 | ENSNLEP00000020085 | ENSNLEP00000048945 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Receptor protein-tyrosine kinase. | 0.997 |
| EGF | ERBB3 | ENSNLEP00000020085 | ENSNLEP00000047229 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Erb-b2 receptor tyrosine kinase 3. | 0.997 |
| EGF | ERBB4 | ENSNLEP00000020085 | ENSNLEP00000008780 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Receptor protein-tyrosine kinase. | 0.990 |
| EGF | EREG | ENSNLEP00000020085 | ENSNLEP00000009683 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Epiregulin. | 0.808 |
| EGF | HBEGF | ENSNLEP00000020085 | ENSNLEP00000011230 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Heparin binding EGF like growth factor. | 0.890 |
| EGF | MET | ENSNLEP00000020085 | ENSNLEP00000024614 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.885 |
| EGF | NTRK1 | ENSNLEP00000020085 | ENSNLEP00000047218 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Tyrosine-protein kinase receptor. | 0.945 |
| EGF | TGFA | ENSNLEP00000020085 | ENSNLEP00000012418 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Transforming growth factor alpha. | 0.988 |