| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGMO | FA2H | ENSNLEP00000019850 | ENSNLEP00000009771 | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.738 |
| CH25H | FA2H | ENSNLEP00000022520 | ENSNLEP00000009771 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.711 |
| CH25H | SC5D | ENSNLEP00000022520 | ENSNLEP00000043080 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.945 |
| EHMT1 | FA2H | ENSNLEP00000011297 | ENSNLEP00000009771 | Euchromatic histone lysine methyltransferase 1. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.658 |
| EHMT1 | PCCB | ENSNLEP00000011297 | ENSNLEP00000032647 | Euchromatic histone lysine methyltransferase 1. | Propionyl-CoA carboxylase subunit beta. | 0.602 |
| EHMT1 | SERPINF2 | ENSNLEP00000011297 | ENSNLEP00000020818 | Euchromatic histone lysine methyltransferase 1. | Serpin family F member 2; Belongs to the serpin family. | 0.678 |
| FA2H | AGMO | ENSNLEP00000009771 | ENSNLEP00000019850 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. | 0.738 |
| FA2H | CH25H | ENSNLEP00000009771 | ENSNLEP00000022520 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.711 |
| FA2H | EHMT1 | ENSNLEP00000009771 | ENSNLEP00000011297 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Euchromatic histone lysine methyltransferase 1. | 0.658 |
| FA2H | FAXDC2 | ENSNLEP00000009771 | ENSNLEP00000020162 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | 0.711 |
| FA2H | MSMO1 | ENSNLEP00000009771 | ENSNLEP00000031264 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | 0.711 |
| FA2H | PCCB | ENSNLEP00000009771 | ENSNLEP00000032647 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Propionyl-CoA carboxylase subunit beta. | 0.693 |
| FA2H | SC5D | ENSNLEP00000009771 | ENSNLEP00000043080 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.601 |
| FA2H | SERPINF2 | ENSNLEP00000009771 | ENSNLEP00000020818 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Serpin family F member 2; Belongs to the serpin family. | 0.685 |
| FA2H | SLC4A8 | ENSNLEP00000009771 | ENSNLEP00000021577 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Anion exchange protein. | 0.658 |
| FA2H | TIMM50 | ENSNLEP00000009771 | ENSNLEP00000017438 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.625 |
| FAXDC2 | FA2H | ENSNLEP00000020162 | ENSNLEP00000009771 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.711 |
| FAXDC2 | SC5D | ENSNLEP00000020162 | ENSNLEP00000043080 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.945 |
| MSMO1 | FA2H | ENSNLEP00000031264 | ENSNLEP00000009771 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.711 |
| MSMO1 | SC5D | ENSNLEP00000031264 | ENSNLEP00000043080 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.958 |
STRING v12.5 is now available!
