Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRKG2cGMP-dependent protein kinase. (762 aa)    
Predicted Functional Partners:
MRVI1
Murine retrovirus integration site 1 homolog.
   
 0.985
VASP
Vasodilator stimulated phosphoprotein.
    
 0.959
PRKG1
cGMP-dependent protein kinase.
  
  
 
0.946
KCNMA1
Potassium calcium-activated channel subfamily M alpha 1.
   
 
 0.943
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
 0.930
GTF2I
General transcription factor IIi.
    
 0.930
KCNU1
Potassium calcium-activated channel subfamily U member 1.
   
 
 0.930
PPP1R17
Protein phosphatase 1 regulatory subunit 17.
    
 0.930
CREB1
cAMP responsive element binding protein 1.
    
 0.927
RGS2
Regulator of G protein signaling 2.
    
 0.927
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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