STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VLDLRVery low density lipoprotein receptor. (873 aa)    
Predicted Functional Partners:
RELN
Reelin.
    
 0.999
APOE
Apolipoprotein E.
    
 0.965
DAB1
DAB adaptor protein 1.
    
 0.958
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.882
SH3KBP1
SH3 domain containing kinase binding protein 1.
     
 0.878
APOB
Apolipoprotein B.
    
 0.858
LIPC
Lipase C, hepatic type.
    
 0.836
CLU
Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
    
 0.803
LRPAP1
LDL receptor related protein associated protein 1.
    
 
 0.785
LRP8
LDL receptor related protein 8.
  
 
 
0.752
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (36%) [HD]