Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VLDLRVery low density lipoprotein receptor. (873 aa)    
Predicted Functional Partners:
RELN
Reelin.
    
 0.999
DAB1
DAB adaptor protein 1.
    
 0.999
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.968
PIK3R2
Uncharacterized protein.
    
 0.925
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
     
 0.924
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
     
 0.924
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.923
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.922
PIK3R3
Phosphoinositide-3-kinase regulatory subunit 3.
    
 0.920
APOE
Apolipoprotein E.
    
 0.906
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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