| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGR1 | EGR2 | ENSNLEP00000010928 | ENSNLEP00000044877 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Early growth response 2. | 0.965 |
| EGR1 | ENSNLEP00000029200 | ENSNLEP00000010928 | ENSNLEP00000029200 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | C2H2-type domain-containing protein. | 0.821 |
| EGR1 | EP300 | ENSNLEP00000010928 | ENSNLEP00000035934 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | E1A binding protein p300. | 0.871 |
| EGR1 | FOS | ENSNLEP00000010928 | ENSNLEP00000047435 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.971 |
| EGR1 | FOSB | ENSNLEP00000010928 | ENSNLEP00000002506 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.953 |
| EGR1 | IER2 | ENSNLEP00000010928 | ENSNLEP00000046712 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Immediate early response 2. | 0.841 |
| EGR1 | JUN | ENSNLEP00000010928 | ENSNLEP00000017965 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.946 |
| EGR1 | JUNB | ENSNLEP00000010928 | ENSNLEP00000034846 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | JunB proto-oncogene, AP-1 transcription factor subunit. | 0.945 |
| EGR1 | MAPK1 | ENSNLEP00000010928 | ENSNLEP00000027273 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.924 |
| EGR1 | NAB1 | ENSNLEP00000010928 | ENSNLEP00000025478 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | NGFI-A binding protein 1. | 0.889 |
| EGR2 | EGR1 | ENSNLEP00000044877 | ENSNLEP00000010928 | Early growth response 2. | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | 0.965 |
| EGR2 | ENSNLEP00000029200 | ENSNLEP00000044877 | ENSNLEP00000029200 | Early growth response 2. | C2H2-type domain-containing protein. | 0.568 |
| EGR2 | EP300 | ENSNLEP00000044877 | ENSNLEP00000035934 | Early growth response 2. | E1A binding protein p300. | 0.924 |
| EGR2 | FOS | ENSNLEP00000044877 | ENSNLEP00000047435 | Early growth response 2. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.733 |
| EGR2 | FOSB | ENSNLEP00000044877 | ENSNLEP00000002506 | Early growth response 2. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.867 |
| EGR2 | JUN | ENSNLEP00000044877 | ENSNLEP00000017965 | Early growth response 2. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.551 |
| EGR2 | JUNB | ENSNLEP00000044877 | ENSNLEP00000034846 | Early growth response 2. | JunB proto-oncogene, AP-1 transcription factor subunit. | 0.495 |
| EGR2 | NAB1 | ENSNLEP00000044877 | ENSNLEP00000025478 | Early growth response 2. | NGFI-A binding protein 1. | 0.673 |
| ENSNLEP00000029200 | EGR1 | ENSNLEP00000029200 | ENSNLEP00000010928 | C2H2-type domain-containing protein. | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | 0.821 |
| ENSNLEP00000029200 | EGR2 | ENSNLEP00000029200 | ENSNLEP00000044877 | C2H2-type domain-containing protein. | Early growth response 2. | 0.568 |
