Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Tyrosine-protein kinase. (1132 aa)    
Predicted Functional Partners:
EPOR
Erythropoietin receptor; Receptor for erythropoietin.
    
 0.999
IFNGR2
Interferon gamma receptor 2.
    
 0.998
STAT3
Signal transducer and activator of transcription.
   
 0.998
CSF2RB
Colony stimulating factor 2 receptor beta common subunit.
   
 0.998
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
    
 0.998
GHR
Growth hormone receptor.
    
 0.998
SOCS1
Suppressor of cytokine signaling 1.
    
 0.997
IL23R
Interleukin 23 receptor.
    
 0.997
M3ZBW0_NOMLE
SH2 domain-containing protein.
   
 0.996
STAT1
Signal transducer and activator of transcription.
   
 0.996
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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