Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNFCyclin F; Belongs to the cyclin family. (786 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.973
CCP110
Centriolar coiled-coil protein 110.
    
 
 0.961
RBX1
Ring-box 1.
    
 0.936
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.922
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.903
ENSNLEP00000029811
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.903
RRM2
Ribonucleotide reductase regulatory subunit M2.
   
 
 0.881
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.868
ESPL1
Extra spindle pole bodies like 1, separase.
   
  
 0.866
ENSNLEP00000042252
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.866
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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