Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD68CD68 molecule. (354 aa)    
Predicted Functional Partners:
GRN
Granulin precursor.
   
 
 0.800
IL6
Uncharacterized protein.
      
 0.782
APOE
Apolipoprotein E.
  
  
 0.768
CD4
CD4 molecule.
      
 0.763
TREM2
Ig-like domain-containing protein.
   
  
 0.754
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.752
C1QA
Complement C1q A chain.
   
  
 0.732
TYROBP
Uncharacterized protein.
   
  
 0.725
GFAP
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 
 0.721
CX3CR1
C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.714
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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