STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEFVMEFV innate immuity regulator, pyrin. (781 aa)    
Predicted Functional Partners:
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 0.996
PYCARD
PYD and CARD domain containing.
    
0.994
NLRP1
NLR family pyrin domain containing 1.
   
 0.969
AIM2
Absent in melanoma 2.
    
 0.966
NLRC4
NLR family CARD domain containing 4.
    
 
 0.952
PKN2
Uncharacterized protein.
    
 0.921
ENSNLEP00000042279
Uncharacterized protein.
    
 0.921
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 0.915
RPS6KA6
Ribosomal protein S6 kinase.
   
 
  0.901
RPS6KA1
Ribosomal protein S6 kinase.
   
 
  0.901
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.