MEFV protein (Nomascus leucogenys) - STRING interaction network

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Score

MEFV

MEFV innate immuity regulator, pyrin. (781 aa)

Predicted Functional Partners:

PYCARD

0.995

CASP1

0.989

PKN1

0.931

PKN2

0.930

LOC100582927

0.930

RIPK1

0.927

CASP8

0.921

RIPK3

0.919

PSTPIP1

0.918

FADD

0.915

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP1	CASP8	ENSNLEP00000044525	ENSNLEP00000040588	Caspase 1; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.973
CASP1	FADD	ENSNLEP00000044525	ENSNLEP00000012731	Caspase 1; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.916
CASP1	MEFV	ENSNLEP00000044525	ENSNLEP00000011730	Caspase 1; Belongs to the peptidase C14A family.	MEFV innate immuity regulator, pyrin.	0.989
CASP1	PYCARD	ENSNLEP00000044525	ENSNLEP00000019741	Caspase 1; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.998
CASP1	RIPK1	ENSNLEP00000044525	ENSNLEP00000013466	Caspase 1; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.901
CASP1	RIPK3	ENSNLEP00000044525	ENSNLEP00000018788	Caspase 1; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 3.	0.909
CASP8	CASP1	ENSNLEP00000040588	ENSNLEP00000044525	Caspase 8; Belongs to the peptidase C14A family.	Caspase 1; Belongs to the peptidase C14A family.	0.973
CASP8	FADD	ENSNLEP00000040588	ENSNLEP00000012731	Caspase 8; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.999
CASP8	MEFV	ENSNLEP00000040588	ENSNLEP00000011730	Caspase 8; Belongs to the peptidase C14A family.	MEFV innate immuity regulator, pyrin.	0.921
CASP8	PYCARD	ENSNLEP00000040588	ENSNLEP00000019741	Caspase 8; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.992
CASP8	RIPK1	ENSNLEP00000040588	ENSNLEP00000013466	Caspase 8; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.999
CASP8	RIPK3	ENSNLEP00000040588	ENSNLEP00000018788	Caspase 8; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 3.	0.998
FADD	CASP1	ENSNLEP00000012731	ENSNLEP00000044525	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 1; Belongs to the peptidase C14A family.	0.916
FADD	CASP8	ENSNLEP00000012731	ENSNLEP00000040588	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 8; Belongs to the peptidase C14A family.	0.999
FADD	MEFV	ENSNLEP00000012731	ENSNLEP00000011730	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	MEFV innate immuity regulator, pyrin.	0.915
FADD	PYCARD	ENSNLEP00000012731	ENSNLEP00000019741	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	PYD and CARD domain containing.	0.831
FADD	RIPK1	ENSNLEP00000012731	ENSNLEP00000013466	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Receptor interacting serine/threonine kinase 1.	0.999
FADD	RIPK3	ENSNLEP00000012731	ENSNLEP00000018788	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Receptor interacting serine/threonine kinase 3.	0.995
LOC100582927	MEFV	ENSNLEP00000044640	ENSNLEP00000011730	Protein kinase domain-containing protein.	MEFV innate immuity regulator, pyrin.	0.930
LOC100582927	PKN1	ENSNLEP00000044640	ENSNLEP00000025452	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.926

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