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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CREBBPCREB binding protein. (2442 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.999
NCOA3
Nuclear receptor coactivator.
   
 0.999
CREB1
cAMP responsive element binding protein 1.
   
 0.999
NCOA1
Nuclear receptor coactivator.
   
 0.999
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.999
EP300
E1A binding protein p300.
  
0.998
NCOA2
Nuclear receptor coactivator.
   
 0.997
STAT2
Signal transducer and activator of transcription.
    
 0.997
KAT2B
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.993
IRF3
IRF tryptophan pentad repeat domain-containing protein.
    
 0.991
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.