Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F1E2F transcription factor 1. (391 aa)    
Predicted Functional Partners:
RB1
RB transcriptional corepressor 1.
   
 0.998
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.996
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.996
RBL1
RB transcriptional corepressor like 1.
   
 0.994
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.993
TFDP2
Transcription factor.
   
 0.993
TFDP1
Transcription factor.
   
 0.984
E2F2
E2F transcription factor 2.
  
 
0.984
RBL2
RB transcriptional corepressor like 2.
   
 0.980
E2F3
E2F transcription factor 3.
  
 
0.975
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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