Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHMP4BCharged multivesicular body protein 4B. (224 aa)    
Predicted Functional Partners:
CHMP2A
Charged multivesicular body protein 2A.
   
 0.998
PDCD6IP
BRO1 domain-containing protein.
   
 0.995
CHMP2B
Charged multivesicular body protein 2B.
   
 0.995
CHMP5
Charged multivesicular body protein 5.
   
0.990
CHMP4C
Charged multivesicular body protein 4C.
  
 
0.985
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.984
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 0.983
CHMP7
Charged multivesicular body protein 7.
    
 0.983
LOC100586164
Uncharacterized protein.
   
 0.980
CHMP6
Uncharacterized protein.
   
 0.974
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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