STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)    
Predicted Functional Partners:
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.999
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.999
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
  
0.998
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.998
IKBKG
NEMO domain-containing protein.
    
 0.997
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.986
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
    
 0.985
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.978
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.976
TRADD
TNFRSF1A associated via death domain.
     
 0.968
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.