STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (890 aa)    
Predicted Functional Partners:
ERCC1
Uncharacterized protein.
   
 0.996
SLX4
SLX4 structure-specific endonuclease subunit.
   
 0.980
XPA
XPA, DNA damage recognition and repair factor.
    
 0.960
MUS81
MUS81 structure-specific endonuclease subunit.
    
 0.896
FANCG
FA complementation group G.
    
 0.876
FANCF
FA complementation group F.
    
 0.875
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
  
 0.868
G1R7X5_NOMLE
Uncharacterized protein.
   
 0.867
FANCB
FA complementation group B.
   
 0.862
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
   
 0.862
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.